Monday, November 2, 2009

Major signs and symptoms of TB disease

Primary Tuberculosis infection usually does not have symptoms. However, if symptoms due occur they may include cough (sometimes producing phlegm), coughing up blood, excessive sweating especially at night, fatigue, fever, and unintentional weight loss. Also breathing difficulty, chest pain, and wheezing may occur.
In a prospective cohort study of “new TB converters” living in Faroe Islands off the coast of Norway from 1932 to 1946, the following s/sx and their respective frequencies were found,
  • Low grade fever, 70%
    a. Could be as high as 39ºC
    b. Lasted for an average of 2 to 3 weeks
    c. Resolved by 10 weeks in 98% of patients
  • Chest pain and painful respiration, 25%
    a. One-half of those with painful respiration
  • Pain worsen upon swallowing , Some
  • Fatigue, Rare
  • Cough, Rare
  • Arthralgias, Rare
  • Pharyngitis, Rare

With primary TB disease, the most common chest X-ray findings in the order of frequencies are, 1) hilar adenopathy, 2) pleural effusion, and 3) pulmonary infiltrates. It is worthwhile to note here that cases with pulmonary infiltrates, 43% have pleural effusion and 33% have lower lobes infiltrates.

References

http://www.cdc.gov/tb/topic/basics/default.htm#difference

Medline Plus: http://www.nlm.nih.gov/medlineplus/ency/article/000077.htm

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